Investigator Guidance
Additional Information and Sample Documents for Housing and Care of Animals
- Housing of Animals Best Practices (Best Practices)
- SOP – Housing of Mice in Static Cages (Template)
- Work Schedule – Housing of Mice in Static Cages (Example)
- SOP – Housing of Mice in Ventilated Cages (Template)
- Work Schedule – Housing of Mice in Ventilated Cages (Example)
- SOP – Housing of Rats in Ventilated Cages (Template)
- Work Schedule – Housing of Rats in Ventilated Cages (Example)
- Emergency Plan for Satellite Housing (Template)
- Temperature Excursion Reporting Log (Example)
- SOP – Housing of Aquatic Species (Template)
- Work Schedule – Housing of Aquatic Species (Example)
Instructions and Additional Information on Policies
- Anesthesia Machine Checklist
- Body Condition Score Chart (Lab Animal Sciences 1999) (Additional Information)
- Guidance for IACUC Policy on Movement of Animals
- How to Prepare an Animal Use Protocol (Instructions)
- How to Report Animal Numbers Manually (Instructions)
- Investigating Animal Concerns Flow Diagram
NIH Office of Laboratory Animal Welfare Information
- Grant Congruency Review
- OLAW Frequently Asked Questions
- OLAW Brochure – What Investigators Need to Know about the Use of Animals communicates to investigators their responsibilities under PHS Grants Policy and PHS Policy on Humane Care and Use of Laboratory Animals. “What Investigators Need to Know About the Use of Animals” provides an overview of investigator responsibilities when conducting research with animals. You will learn about the PHS Policy requirements, what you need to describe in your grant application and your IACUC animal study protocol, and guidance for conducting your research to avoid noncompliance.
- Preparing the Vertebrate Animal Section (VAS) for National Institutes of Health (NIH) –requirements for completing the VAS of grant applications, cooperative agreements and contract proposals have changed (NOT-OD-16-006) along with some features of 2016 grant application guidance, forms and instructions (NOT-OD-16-004) . Additional information, including a checklist, detailed instructions and links to worksheets are available at the NIH Office for Laboratory Animal Welfare webpage Vertebrate Animals Section.
Information on Areas of Potential Pain and Distress
- Antibody Production (ARENA Institutional Animal Care and Use Committee Guidebook pages 125-129)
- Guidelines for Ascites Production in Mice (Monoclonal Antibody Production)
- Guidelines for the Use of Adjuvants in Research (Special emphasis on Freund’s Adjuvant)
Information on Alternatives to Animal Testing and Databases to Conduct Searches
- As part of the animal use protocol, PIs are required to consider alternatives to procedures that may cause more than momentary or slight pain or distress. See USDA Policy 12 for more information.
- Guidance on Alternative Endpoints
- Assistance at The Ohio State University Libraries
- Fact Sheet – MEDLINE, PubMed, and PubMed Central: How are they different?
- ALTBIB (National Library of Medicine)
- ALTWEB
- Animal Welfare Information Center (AWIC)
- AGRICOLA (AGRICultural OnLine Access, USDA)
- CAB Direct
- OhioLINK
- PUBMED (National Library of Medicine)
- TOXNET (National Library of Medicine)
Investigator/Staff Guidance for Inspections
- Investigator/Staff Guidance for FDA Inspections
- Laboratory Self-Assessment for IACUC Approved Activities
Organizations
- Association for Assessment and Accreditation of Laboratory Animals (AAALAC)
- American Association for Laboratory Animal Science (AALAS)
- American Society of Laboratory Animal Practitioners (ASLAP)
- American College of Laboratory Animal Medicine (ACLAM)
- Institute for Laboratory Animal Research (ILAR)
- Public Responsibility in Medicine and Research (PRIM&R)
- Scientist Center for Animal Welfare (SCAW)
