Office of Responsible Research Practices
The Ohio State University

Single IRB (sIRB)

For information on updates recently added to Buck-IRB to facilitate Single IRB (SIRB) submissions, please see Updates to the Buck-IRB system


Using Ohio State as the Single IRB (sIRB) for Multi-Site Research

Below are resources and forms for investigators using an Ohio State University IRB as the IRB of record or as a sIRB for multi-site human subjects research.  For questions regarding the sIRB process at Ohio State, contact IRBAgreements@osu.edu.

IRB Authorization Agreement – FWA Holding Institutions (IAA OHRP template)
This type of IRB Authorization Agreement (IAA) authorizes a FWA holding institution who is not a SMART IRB participating institution to rely on an Ohio State IRB for review responsibilities.  The IAA document describes the division of responsibilities between the relying institution and the Ohio State IRB.

IRB Authorization Agreement – SMART IRB Participating Institutions
Ohio State prefers to use the SMART IRB Online Reliance System or a SMART IRB Letter of Acknowledgement (Ohio State template) for SMART IRB participating institutions who rely on an Ohio State IRB.

Institutional Profile and Study Specific Local Context Worksheet for Relying Sites (Ohio State form)
New non-Ohio State research site – use this form to identify and report the local context considerations for a non-Ohio State research site which will be engaged in research and rely on an Ohio State IRB.  This form provides an institutional profile and study specific considerations.  This form should be submitted when the participating site will be recruiting or obtaining consent from research subjects or if any research interventions or subject interactions will occur at the site.

Study Specific Local Context Worksheet for Relying Sites (Ohio State form)
Existing non-Ohio State research site – use this form to identify and report the local context considerations for a non-Ohio State research site which already has an institutional profile registered in Buck-IRB.  This form should be submitted for each study when the participating site will be recruiting or obtaining consent from research subjects or if any research interventions or subject interactions will occur at the site.