Changes to Approved Protocols (Amendments)
The Institutional Animal Care and Use Committee (IACUC) must be notified of any proposed significant change to an Animal Use Protocol (AUP). Proposed changes to an AUP must be reviewed and approved by the IACUC. A proposed change to AUP at The Ohio State University (OSU) may not be initiated until notification of IACUC approval has been received.
Investigators who wish to propose a change to a currently active AUP should submit a request using the most recent version of the IACUC Amendment Request form (available at: http://orrp.osu.edu/animalsubjects/forms.cfm) that, when properly completed, will provide the information needed to enable the IACUC to evaluate the proposed change. After completeness of an Amendment Request is verified, the amendment is scheduled for the next available IACUC review based on the review criteria outlined below.
Amendment Requests proposing activities or changes that do not involve survival surgery on a USDA-covered species, unrelieved pain or distress (including prolonged restraint), death as an endpoint, multiple survival surgery, or the use of primates may be evaluated by designated member review. Amendment Requests proposing activities or changes that involve survival surgery on a USDA-covered species, unrelieved pain or distress (including prolonged restraint), death as an endpoint, multiple survival surgery, or use of primates (along with any other Amendment Request for which an IACUC member has called for full committee review) are evaluated at the next scheduled convened IACUC meeting.
Designated member review for amendments typically occurs twice a month. Convened IACUC meetings typically occur once per month.
Proposed change requests that only involve adding or removing personnel, not including the Principal Investigator, on an AUP should be submitted to the IACUC utilizing the IACUC Personnel Addition/Removal Form. A change in the Principal Investigator of an Animal Use Protocol must be processed utilizing the IACUC Amendment Request Form.
